Translational neuroimaging research in pediatric obsessive-compulsive disorder

Neuroimaging and neuropsychological findings in pediatric obsessive–compulsive disorder: a review and developmental considerations

Genetic and imaging strategies in obsessive-compulsive disorder: potential implications for treatment development.

In recent years, advances in brain research have resulted in a striking strategic shift in studies designed to develop new, effective treatments for neuropsychiatric disorders. This involves a multidisciplinary approach with recursive interactions among respective disciplines with the ultimate goal of contributing to treatment development. In this review we focus on treatment implications of br...

A review of obsessive-compulsive disorder in children and adolescents

This article is a review of recent literature on obsessive-compulsive disorder in the pediatric population. Areas covered include: a brief historical perspective, clinical presentation in relation to symptoms found in different age groups, epidemiology, psychiatric comorbidity, etiology (with regards to genetics, neuroimaging, and familial factors), clinical course and prognosis, and treatment,...

Co-Morbidity of Obsessive Compulsive Disorder and Tourette Syndrome

Objectives: Tourette syndrome is a disease with vocal and motor tics. This disorder is co-morbid with many psychiatric disorders, among which obsessive-compulsive disorder is the most common. Methods: During a one-year period, 30 patients with Tourette disorder were studied at an adolescent psychiatry referral clinic. It was an analytical-descriptive study. Subjects were selected by convenie...

Brain imaging in pediatric obsessive-compulsive disorder.

OBJECTIVE To review progress in understanding pediatric obsessive-compulsive disorder (OCD). The focus is on the frontal-striatal-thalamic model of OCD, neurobiological and genetic studies of the disorder, and their influence on recent advances in treatment. METHOD Computerized literature searches were conducted with the key words "obsessive-compulsive disorder" in conjunction with "pediatric...